2011

Role of Sphingosine 1-phosphate in cancer: Seeking the Golden Sword of Hercules. - Professor Nigel Pyne
A role for sumoylation in nuclear organisation and DNA repair. - Dr. Helder Ferreira
Metal matters: iron and copper in the bacterial cell. - Professor Nick Le Brun
The genomics of drug sensitivityin cancer. - Mathew Garnett
Investigating protein amyloid self-assembly and conformational change by ion mobility spectrometry mass spectrometry. - Dr. David Smith
Strategies for Supplying Proteins for Structural Studies - Richard Bazin
Expanding the repertoire of enzyme catalysis. - Professor Alan Berry
Metals, minerals and microbes: geomicrobiology and bioremediation. - Professor Geoffrey Gadd, FRSE
Cell signalling in the human parasite Schistosoma mansoni - Dr. Anthony J. Walker
Metabolomics and Raman spectroscopy: challenges and opportunities for the analysis of complex biological systems. - Professor Roy Goodacre
Drug-adapted cancer cell lines as resistance models - Professor Martin Michaelis
Regulation of lipid and membrane biogenesis by lipins. - Dr. Symeon Siniossoglou
Chromosome translocations in breast cancer and other common epithelial cancers - Dr. Paul Edwards
Molecular mayhem! Dynamics, defects and disorder - Dr. Sarah Harris
How safe can we make IVF? - Dr. Alan Thornhill
Biophysics of amyloid growth. - Dr. Tuomas P.J. Knowles
Investigating the molecular mechanism of endocytosis. - Professor Kathryn Ayscough
The kynurenine pathway in neurodegeneration: mechanisms and therapeutic targets. - Dr. Flav Giorgini
Slipping and sliding: a single molecule view of molecular motors. - Dr. Neil Kad
Using simple model organisms to study ageing and neurodegeneration. - Professor Alan Morgan
Nitric oxide tolerance in pathogenic bacteria. - Dr. Mark Shepherd
Modulation and modification of Rab proteins by Legionella pneumophila effector proteins. - Prof. Dr. Roger S. Goody
Coupling the molecular kinesin-1 to new cargo, functions and diseases - Dr. Mark Dodding
Life with little ligands: the microbiology of oxygen, nitric oxide and carbon monoxide. - Professor Robert Poole
The good, the bad and the degenerates: what metabolism tell us about cell viability. - Dr. Roger G. Sturmey
Cell cycle regulated transcription and control of genome integrity. - Dr. Rob de Bruin
Systems Biology Approaches to Inflammation and Cancer specific Signaling Networks. - Prof. Dr. Thomas Sauter
The good, the bad and the degenerates: what metabolism tell us about cell viability. - Dr. Roger G. Sturmey
Culture adapted human embryonic stem cells: Thugs or Saints? - Professor Peter Andrews
An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis. - Dr. Fulvio Reggiori
Fibril fragmentation in amyloid assembly and cytotoxicity - When size matters. - Dr. Wei-Feng Xue
CANCELLED - Dr. Neil Kad
Peroxisome dynamics in Saccharomyces cerevisiae: from the cradle to grave. - Dr. Ewald Hettema
The challenges and opportunities of understanding protein folding and protein misfolding in health and disease. - Professor Sheena Radford
Regulating mRNA binding to the ribosome in mammalian cells - Professor Simon Morley
Application of proteomics tools to study dynamic changes in sub cellular protein location. - Dr. Kathryn Lilley
Chromosomes in the mammalian nucleus: unravelling clues that reveal how nuclear structure and function are linked - Dr. Dean Jackson
The genes, pathways and microbes that make the smell of the seaside. - Dr. Jonathan Todd
Food for thought: The bacterial queuosine molecule and its influence on the metabolism and behaviour of higher eukaryotes. - Dr. Vincent Kelly
Individuality of yeast cells, their stress resistances and virulence - Dr. Simon Avery
MicroRNAs from mechanism to biology. - Dr. Martin Bushell
Nanobodies, the next generation antibody products for research, diagnosis and therapy. - Dr. Serge Muyldermans
Translational control: recycling eIF2 in health, stress and disease. - Dr. Graham Pavitt

2010

Role of Sphingosine 1-phosphate in cancer: Seeking the Golden Sword of Hercules. - Professor Nigel Pyne
A role for sumoylation in nuclear organisation and DNA repair. - Dr. Helder Ferreira
Metal matters: iron and copper in the bacterial cell. - Professor Nick Le Brun
The genomics of drug sensitivityin cancer. - Mathew Garnett
Investigating protein amyloid self-assembly and conformational change by ion mobility spectrometry mass spectrometry. - Dr. David Smith
Strategies for Supplying Proteins for Structural Studies - Richard Bazin
Expanding the repertoire of enzyme catalysis. - Professor Alan Berry
Metals, minerals and microbes: geomicrobiology and bioremediation. - Professor Geoffrey Gadd, FRSE
Cell signalling in the human parasite Schistosoma mansoni - Dr. Anthony J. Walker
Metabolomics and Raman spectroscopy: challenges and opportunities for the analysis of complex biological systems. - Professor Roy Goodacre
Drug-adapted cancer cell lines as resistance models - Professor Martin Michaelis
Regulation of lipid and membrane biogenesis by lipins. - Dr. Symeon Siniossoglou
Chromosome translocations in breast cancer and other common epithelial cancers - Dr. Paul Edwards
Molecular mayhem! Dynamics, defects and disorder - Dr. Sarah Harris
How safe can we make IVF? - Dr. Alan Thornhill
Biophysics of amyloid growth. - Dr. Tuomas P.J. Knowles
Investigating the molecular mechanism of endocytosis. - Professor Kathryn Ayscough
The kynurenine pathway in neurodegeneration: mechanisms and therapeutic targets. - Dr. Flav Giorgini
Slipping and sliding: a single molecule view of molecular motors. - Dr. Neil Kad
Using simple model organisms to study ageing and neurodegeneration. - Professor Alan Morgan
Nitric oxide tolerance in pathogenic bacteria. - Dr. Mark Shepherd
Modulation and modification of Rab proteins by Legionella pneumophila effector proteins. - Prof. Dr. Roger S. Goody
Coupling the molecular kinesin-1 to new cargo, functions and diseases - Dr. Mark Dodding
Life with little ligands: the microbiology of oxygen, nitric oxide and carbon monoxide. - Professor Robert Poole
The good, the bad and the degenerates: what metabolism tell us about cell viability. - Dr. Roger G. Sturmey
Cell cycle regulated transcription and control of genome integrity. - Dr. Rob de Bruin
Systems Biology Approaches to Inflammation and Cancer specific Signaling Networks. - Prof. Dr. Thomas Sauter
The good, the bad and the degenerates: what metabolism tell us about cell viability. - Dr. Roger G. Sturmey
Culture adapted human embryonic stem cells: Thugs or Saints? - Professor Peter Andrews
An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis. - Dr. Fulvio Reggiori
Fibril fragmentation in amyloid assembly and cytotoxicity - When size matters. - Dr. Wei-Feng Xue
CANCELLED - Dr. Neil Kad
Peroxisome dynamics in Saccharomyces cerevisiae: from the cradle to grave. - Dr. Ewald Hettema
The challenges and opportunities of understanding protein folding and protein misfolding in health and disease. - Professor Sheena Radford
Regulating mRNA binding to the ribosome in mammalian cells - Professor Simon Morley
Application of proteomics tools to study dynamic changes in sub cellular protein location. - Dr. Kathryn Lilley
Chromosomes in the mammalian nucleus: unravelling clues that reveal how nuclear structure and function are linked - Dr. Dean Jackson
The genes, pathways and microbes that make the smell of the seaside. - Dr. Jonathan Todd
Food for thought: The bacterial queuosine molecule and its influence on the metabolism and behaviour of higher eukaryotes. - Dr. Vincent Kelly
Individuality of yeast cells, their stress resistances and virulence - Dr. Simon Avery
MicroRNAs from mechanism to biology. - Dr. Martin Bushell
Nanobodies, the next generation antibody products for research, diagnosis and therapy. - Dr. Serge Muyldermans
Translational control: recycling eIF2 in health, stress and disease. - Dr. Graham Pavitt
Robustness analysis of stochastic biomolecular networks. - Dr. Jongrae Kim
Getting the message across: dissectiong cytoskeletal mRNA transport mechanisms in vivo and in vitro. - Dr. Simon Bullock
Post-translational regulation of PABP function: implications for meiosis and mitosis. - Dr. Matthew Brook
An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis. - Dr. Fulvio Reggiori
Conformation states of membrane proteins - Professor James H. Naismith
Molecular and cellular dissection of class-1 myosins. - Prof. Dr. Georgios Tsiavaliaris
Control engineering approaches to systems biology reserch. - Professor Declan Bates
Mammalian chromosome evolution. - Professor Denis Larkin
Games of hide-and-seek at the E. coli cell surface. - Dr. Christophe Beloin
Antibodies and lectins that inhibit viral entry: new tools for prevention of AIDS. - Dr. Alexander Wlodawer
Assembly of the signal recognition particle and quality control of its RNA. - Dr. Jeremy Brown
Cytochrome cd1: how a nitrite reductase important for the environment works and is assembled. - Professor Stuart Ferguson
Protein misfolding: insights into amyloid toxicity in a yeast model - Professor Christophe Cullin
Regulation of DNA Replication Origin Activity. - Dr. Conrad Nieduszynski
Human in vitro models of EPEC and EHEC infection. - Dr. Stephanie Schuller
CyDisCo: An efficient method for making disulfide bond containing proteins in the cytoplasm of E.coli - Prof. Lloyd Ruddock
The Cytokinetic Phragmoplast: structure, proteomics, evolution and cytoskeleton component. - Professor Patrick Hussey
Staphylococcus aureus flavohaemoglobin: dark side and light side of a protein. - Dr. Ligia M. Saraiva
Unconventional levers used by unconventional myosins. - Professor Peter Knight
Unraveling the molecular mechanisms of neurodegeneration: from humanized yeast cells to diagnostics and drugs. - Prof. Dr. Joris Winderickx
Microtubule-actin filament coupling in growth cone pathfinding. - Professor Phillip Gordon-Weeks
Structural aspects of human papilloma virus oncoproteins. - Dr. Oliver Ohlenschlager
Interplay between the actin cytoskeleton and membrane phosphoinositides in cell adhesion and migration. - Professor Pekka Lappalainen
New analysis strategies reveal many additional protein coding loci in the S. pombe genome. - Dr. Crispin Miller
The effect of genomic rearrangements on the evolution of function in the immune system. - Professor Jim Kaufman
Survival in the host-stress signalling in the human fungal pathogen Candida albicans. - Dr. Janet Quinn
The new science of ageing. - Professor Linda Partridge
Molecular sponges, biofoams and in-cell NMR: exotic structural biology. - Dr. Brian Smith
Genome-wide responses of the pathogen Candida albicans to host stimuli. - Professor Alistair Brown
A pain in the butt: Understanding the physiology of the food-borne pathogen Campylobacter jejuni. - Professor Dave Kelly

2009

Targeting small molecules to mitochondria. - Dr. Michael P. Murphy
Prion disease: where have all my synapses gone. - Dr. Vincent O'Connor
Fighting antibiotics resistance: NMR structural studies of metallo-beta-lactamases. - Dr. Christian Damblon
Regulation of translation during cell stress. - Professor Anne Willis
Evolution of protein domain families. - Dr. Alex Bateman
Dystroglycan: a multifunctional adhesion receptor. - Professor Steve J. Winder
Systems Biology unravels the mechanism of cellular function - Dr. Najl Valeyev
mTOR complex 1, a master regulator of cell function. - Professor Chris Proud
Myosins and chitin sythases in fungal plant infection. - Professor Gero Steinberg
New beginnings - Expanding the proteome by selection of alternative translation initiation codons. - Dr. Mark Coldwell
Understanding bio-aggregation from model organisms to environmental applications. - Dr. Catherine Biggs
Structure and function of enzymes for the biosynthesis of heme and chlorophylls. - Prof. Dr. Dieter Jahn
Interactions and Allostery in the Hsp90 Chaperone System. - Dr. Mark A. Williams
Regulation of layer-specific axon targeting in the visual system of Drosophila. - Dr. Iris Salecker
Translational recoding in Saccharomyces cerevisiae. - Dr. Olivier Namy
Overcoming the Embryo. - Professor Austin Smith
The molecular and cell biology of hyphal development in the human fungal pathogen Candida albicans. - Professor Peter Sudbery
Dynamics and rate control in the eukaryotic translation machinery - Professor John McCarthy
MS genetics - "Give us the tools and we will finish the job" - Dr. Stephen Sawcer
A spin on membranes: using MAS-NMR to investigate the interactions between lipids, proteins and ligands - Dr. Mark Lorch
Easing out of a pressure situation - mechanosensitive channels in bacteria - Professor Ian Booth
The many faces of heme in biology - Professor Emma Raven
Developmental pathways from the fungal spore - Professor Nick Read
The chemistry of oxygen sensing in humans - Professor Christopher J. Schofield
Activation of Protein Kinases by the Hsp90 Molecular Chaperone System - Professor Laurence Pearl, FRS
How do cells ensure that metalloproteins get the correct metal? - Professor Nigel Robinson
The effect of genomic rearrangements on the evolution of function in the immune system. - Professor Jim Kaufman
Structural analysis of a translational repression complex. - Dr. Tom Edwards
What can we learn from fungal molecular biology? Novel regulatory mechanisms of eukaryotic transcription factors and activation of silent gene clusters. - Prof. Dr. Axel Brakhage

2008

Plant-dinosaur co-evolution: examining the evidence - Dr. Paul M. Barrett
Breast Cancer Genetics - Professor Ellen Solomon
A new perspective on enzyme catalysis - Professor Nigel S. Scrutton
Structural requirements for lignin peroxidase activity: Engineering a redox active Trp in Coprinus cinereus peroxidase - Professor Andrew T. Smith
Staphylococcus aureus:  virulence, carriage and fighting the fat - Professor Simon Foster
Assembly and function of the apoptotic microtubule network - Dr. Jon Lane
Condensin and PP1 regulate chromosome structure and dynamics in mitosis - Dr. Paola Vagnarelli
Carbonic anhydrases: novel applications for inhibitors and activators - Dr. Claudiu Supuran
Spindle formation in female meiosis - Dr. Hiro Ohkura
Life after genome-wide association studies - Dr. Ines Barroso
From global gene control to novel gene function:  an acid-induced iron transport system in E. coli O157 - Dr. Simon Andrews
Site selective protein modification for the development of a Glyco-Ruler - Dr. James Errey
Structure and function of calexcitin ­ a neuronal protein involved in learning and memory - Professor John B. Cooper
Science and Sociology of Drug Discovery - Professor Peter Goodfellow
Chlorophyll-proteins: from global photosynthesis to nanopatterning - Professor Neil Hunter
Making an escape: Gap junctions and electrical synapses - Dr. Pauline Phelan
BENT STIFF & LEGLESS – an analysis of cytoskeleton function in fission yeast - Dr. Dan Mulvihill
What does the architecture of amyloid tell us about protein misfolding diseases? - Dr. Louise Serpell
Pairing and segregation of homologous chromosomes during C. elegans meiosis. - Dr. Enrique (Fadri) Martinez-Perez
Macrophage migration and chemotaxis in Drosophila embryos. - Dr. Will Wood
Genetic dissection of the Drosophila circadian clock. - Professor Ralf Stanewsky
Host-microbe interactions in intestinal health and disease. - Professor Simon Carding
Protein folding and misfolding at the endoplasmic reticulum. - Dr. Lisa Swanton
The polyketide acyl carrier protein – a remarkable multi-functional enzyme. - Dr. Matthew Crump
The ins and outs of G0 in yeast. - Prof. Dr. Claudio de Virgilio
Bacterial metabolosomes and intestinal bacteria. - Professor Mike Prentice
The presentation of ubiquitinated substrates to the 26S proteasome. - Dr. Colin Gordon

2007

Novel approaches to the isolation and characterisation of multi-protein assemblies. - Professor David Hornby
Modulators of expanded polyglutamine protein aggregation. - Dr. Anne Bertolotti
The role of cGmP and the cGMP-dependent protein kinase in gametogenesis in the marlaria parasite Plasmodium falciparum. - Dr. David Baker
Cyclic AMP compartmentalization - a key component of signal transduction. - Professor Dermot Cooper
A unique mechanism of microtubule stabilisation by doublecortin. - Dr. Carolyn Moores
Meiosis specific regulation of microtubule organising centre in the fission yeast S. pombe. - Dr. Kayoko Tanaka
Elucidation and manipulation of the biosynthetic pathway to aminoglycoside antibiotics - Dr. Jonathan Spencer
Development of renal systems in the fly - are there parallels with vertebrate nephrogenesis? - Dr. Helen Skaer
Quorum sensing, virulence and the discovery of new antibacterial. - Professor Paul Williams
Structural studies of the dynein motor protein by electron microscopy. - Dr. Stan Burgess
Yeast prions: a novel mode of epigenetic inheritance. - Professor Mick F. Tuite