Steffy Angel Rajamani Girija

PhD in Biochemistry, School of Natural Sciences
 Steffy Angel Rajamani Girija

About

I graduated from SRM Institute of Science and Technology (India) with a B.Tech in Biotechnology and from Edinburgh Napier University (Scotland) with a MSc in Medical Biotechnology. After attending a plethora of internships on various disciplines including Stem Cells handling, Plant cell plasma fusion and also with 2.5 years of experience of In-vitro and In-vivo Diabetic wound healing research along with animal handling (Wistar rats), now I have commenced my PhD in Biochemistry under the supervision of Professor Martin Warren and Professor Mark Smales.

During her Undergraduate and Postgraduate studies, she specialised and was awarded Honorary diploma in Human Anatomy and Physiology, Stem Cells handling.

I also worked as a Visiting researcher in Synthetic biology at University of Edinburgh under the guidance of Dr Elise Cachat(2018).

Research interests

My research works includes
• Comparison of SARS-CoV and SARS-CoV2 Receptor Binding domain to locate a conserved domain within the RBD genome, which will be an efficient candidate for Vaccine development. (MSc Thesis)
• Role of alkaloids from Adhatoda vasica in angiogenesis through nitric oxide signalling cascade.
• Anticancer activity of the crude methanolic extract of Cardiospermum halicacabum.
• Plant protoplasmic fusion from two different plants namely Artabotrys haxapetalus and Couropita guianensis.
• Diabetic wound healing ability of alkaloid extracts from Adathoda vasica on Male albino Wistar rats which were genetically immune deficient and also Diabetic induced.
• Diabetic wound healing property of Adathoda vasica leaf extracts on Human Umblical Vein Endothelial Cells (HUVECs).
• Synthetic Biology using transformed BL21(DE3) E.coli to transfect Human Embryonic Kidney cells (HEK) to express Green Fluorescent Protein on their surface.
• Comparison of Coronavirus spike proteins.
• Generation of Coronavirus protein antigens for development of diagnostics and novel vaccine approaches (current PhD study) 

Teaching

• Metabolism and metabolic Regulation - BI527 (In-lab demonstrator)
• Plant Physiology and Adaptation – BI547 (In-lab demonstrator)
• Skills for Bio-scientists – BIOS3080 (In-lab demonstrator)
• Skills/lab recap – BIOS5320 (In-lab demonstrator)
• Lab skills recap – BIOS6000 (In-lab demonstrator)
• Practical Molecular Biology and Genome editing (Masters) – CRISPR Cas9 – BIOS8590 (In-lab demonstrator) 

Supervision

Supervised by Professor Martin Warren.

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