How do genes work and how can we manipulate them? How can techniques such as whole-genome sequencing and genome editing be applied to detect and treat diseases? This module deals with the flow of genetic information from DNA to RNA to protein in organisms ranging from viruses to humans. You will learn how genetic information is stored in DNA and RNA, how that information is decoded by the cell and how the flow of information is controlled in response to changes in environment or developmental stage. You will compare and contrast mechanisms of gene regulation in prokaryotes and eukaryotes, and explore the latest developments in molecular genetic techniques to analyse and manipulate gene function, and how they can be applied to research on human disease and biomanufacturing of useful biological products with real-world application.
Lecture 22 hours, Workshop 4 hours, Practical 4 hours
Short answer questions worth 40%
Examination worth 60%
Reassessment Method: Like-for-like
For BSc Biomedical Science students (as a requirement of the IBMS accreditation): all component assessments are instead pass-compulsory. Additionally, this module cannot be compensated or condoned as indicated in the course specification.
On successfully completing the module, students will be able to:
1. Examine the key concepts that govern the flow of genetic information from viruses to humans.
2. Apply key concepts of the genetic code and gene structure to solve problems related to gene mutation and manipulation.
3. Analyse and interpret experimental results generated from genetic manipulation of gene function acquired in a laboratory setting.
4. Apply knowledge of key molecular genetics techniques used to real-world problems in health and biomanuacturing.
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